Isothebaine

CAS: 568-21-8

Ref. 3D-FI69752

Product Information

• Name: Isothebaine
• Synonyms: (+)-Isothebaine, (6aS)-5,6,6a,7-Tetrahydro-2,11-dimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-1-ol, (S)-5,6,6a,7-Tetrahydro-2,11-dimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-1-ol, 1-Hydroxy-2,11-dimethoxy-6aα-aporphine, 2,11-Dimethoxy-6aa-aporphin-1-ol, 4H-Dibenzo[de,g]quinolin-1-ol, 5,6,6a,7-tetrahydro-2,11-dimethoxy-6-methyl-, (S)-, 4H-dibenzo[de,g]quinolin-1-ol, 5,6,6a,7-tetrahydro-2,11-dimethoxy-6-methyl-, (6aS)-, 568-21-8, 6aα-Aporphin-1-ol, 2,11-dimethoxy-, NSC 290957

Description

Isothebaine is a benzimidazole compound that acts as a competitive inhibitor of protopine, an enzyme which catalyzes the conversion of tryptophan to 5-hydroxytryptophan. It inhibits the synthesis of serotonin and melatonin. Isothebaine has been shown to have effective analgesic properties in animal models and is used for the treatment of pain. Isothebaine has been shown to have regulatory effects on radiation-induced damage and cervical cancer cell cultures, as well as anti-cancer effects in cell culture models. This drug also inhibits the growth of several types of cancer cells by inhibiting the production of DNA molecules, proteins, and other important cellular components. Isothebaine has also been found to be effective against plant families that are known for causing metabolic disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 311.37 g/mol
• Formula: C₁₉H₂₁NO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H21NO3/c1-20-8-7-12-10-15(23-3)19(21)18-16(12)13(20)9-11-5-4-6-14(22-2)17(11)18/h4-6,10,13,21H,7-9H2,1-3H3/t13-/m0/s1
• InChI key: InChIKey=RQCOQZNIQLKGTN-ZDUSSCGKSA-N
• SMILES: COc1cc2c3c(c1O)-c1c(cccc1OC)C[C@@H]3N(C)CC2