a-Ketoglutaric acid

CAS: 328-50-7

Ref. 3D-FK09820

Product Information

• Name: a-Ketoglutaric acid
• Synonyms: 2-Oxopentanedioic acid2-Oxoglutaric acid, 2-Ketoglutaric acid, 2-Oxo-1,5-pentanedioic acid, 2-Oxoglutaric Acid, 2-Oxoglutarsaure, 2-Oxopentanedioic acid, Acide 2-oxoglutarique, Acido 2-Oxoglutarico, Glutaric acid, 2-oxo-, Nsc 17391, α-Ketoglutaric acid, α-Oxoglutaric acid, α-Oxopentanedioic acid, α-keto-Glutaric acid
• CAS: 328-50-7

Description

a-Ketoglutaric acid is a naturally occurring organic compound that is found in the body as well as in plants. It belongs to the group of organic acids and is produced from the breakdown of amino acids, such as leucine and valine. a-Ketoglutaric acid has been shown to have physiological effects on cells and tissues by inhibiting enzymes involved in energy metabolism. In vitro assays have shown that a-ketoglutaric acid has inhibitory properties against plant metabolism. This drug also inhibits the transcriptional regulation of genes for fatty acid synthesis in human erythrocytes.
A-ketoglutaric acid has also been shown to inhibit glucose production in rat liver cells, which may be due to its ability to bind covalently with proteins or lipids, changing their structures and functions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.1 g/mol
• Formula: C₅H₆O₅
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
• InChI key: InChIKey=KPGXRSRHYNQIFN-UHFFFAOYSA-N
• SMILES: O=C(O)CCC(=O)C(=O)O