H-Leu-Arg-OH acetate salt

CAS: 26607-15-8

Ref. 3D-FL108087

Product Information

• Name: H-Leu-Arg-OH acetate salt
• Synonyms: 124: PN: WO2009132287 SEQID: 194 claimed protein, 1707: PN: WO2007124090 PAGE: 83 claimed protein, 175: PN: WO2011032181 SEQID: 194 unclaimed protein, 182: PN: WO2009114815 SEQID: 194 unclaimed protein, 205: PN: WO2010059829 SEQID: 223 unclaimed protein, 26: PN: EP2161028 PAGE: 10 claimed protein, 44: PN: WO2010045512 SEQID: 43 unclaimed protein, 522: PN: WO2010124259 SEQID: 551 claimed protein, 525: PN: WO2010124262 SEQID: 551 claimed protein, 78: PN: US20070066537 PAGE: 17 claimed protein, <span class="text-smallcaps">L</smallcap>-Arginine, <smallcap>L</span>-leucyl-, <span class="text-smallcaps">L</smallcap>-Arginine, N²-<smallcap>L</span>-leucyl-, <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-arginine, Arginine, N²-<span class="text-smallcaps">L</smallcap>-leucyl-, <smallcap>L</span>-, H-Leu-Arg-OH, L-leucyl-N~5~-(diaminomethylidene)-L-ornithine, leucyl-N~5~-(diaminomethylidene)ornithine

Description

H-Leu-Arg-OH acetate salt is a cyclase inhibitor that is used to treat cancer. It has been shown to inhibit soluble guanylate cyclase, which is an enzyme that converts guanosine triphosphate (GTP) into the second messenger molecule, cyclic guanosine monophosphate (cGMP). Inhibition of this enzyme results in a decrease in the production of cGMP and blood pressure. H-Leu-Arg-OH acetate salt also inhibits delta opioid receptors, which are found on the surface of cells in the brain. This drug binds competitively with delta opioid receptors and blocks the effect of endogenous or exogenous ligands such as enkephalins.

• Brand: Biosynth

Chemical properties

• Molecular weight: 287.36 g/mol
• Formula: C₁₂H₂₅N₅O₃
• Purity: Min. 95%
• Color/Form: Powder