b-Lapachone

CAS: 4707-32-8

Ref. 3D-FL170803

Product Information

• Name: b-Lapachone
• Synonyms: 2,2-Dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione, 2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione, 2H-Naphtho(1,2-b)pyran-5,6-dione, 3,4-dihydro-2,2-dimethyl-, 3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione, Arq-501, Brn 0181499, Lapachone, beta-, Mb 12066, Nsc 26326, Nsc 629749, Sl 11001, beta-Lapachone
• CAS: 4707-32-8

Description

b-Lapachone is a naturally occurring compound that has been shown to be cytotoxic in vitro. It has significant cytotoxicity against HL-60 cells and has been shown to inhibit the activity of enzymes such as cyclin d2, which regulates cell cycle progression, and topoisomerase II, which maintains genomic stability. b-Lapachone also has pro-apoptotic properties, which means it induces programmed cell death (PCD) by activating caspases. This apoptosis can lead to neurodegenerative disorders or brain function changes. Furthermore, b-lapachone has been shown to stimulate mitochondrial functions and polymer compositions, which may have implications for drug delivery systems.

• Brand: Biosynth

Chemical properties

• Molecular weight: 242.27 g/mol
• Formula: C₁₅H₁₄O₃
• Purity: Min. 95%