D,L N-desmethyl venlafaxine

CAS: 149289-30-5

Ref. 3D-FL24819

Product Information

• Name: D,L N-desmethyl venlafaxine
• Synonyms: 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanolNorvenlafaxine, 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexan-1-ol, 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol, Cyclohexanol, 1-[1-(4-methoxyphenyl)-2-(methylamino)ethyl]-, N-Desmethylvenlafaxine, Norvenlafaxine

Description

D,L-N-desmethylvenlafaxine (D,LNDM) is a metabolite of venlafaxine that has been shown to have antidepressant properties in animals. D,LNDM inhibits the synthesis of inflammatory mediators such as prostaglandins and leukotrienes by inhibiting cyclooxygenase-1 and 2 enzymes. The drug is not active against ventricular dysfunction or neuropathic pain. D,LNDM can be prepared from venlafaxine using a variety of methods, including chemical synthesis or extraction from Chinese herbs. The compound is rapidly excreted in urine and cannot be detected in plasma within 24 hours after administration.

• Brand: Biosynth

Chemical properties

• Molecular weight: 263.38 g/mol
• Formula: C₁₆H₂₅NO₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C16H25NO2/c1-17-12-15(16(18)10-4-3-5-11-16)13-6-8-14(19-2)9-7-13/h6-9,15,17-18H,3-5,10-12H2,1-2H3
• InChI key: InChIKey=MKAFOJAJJMUXLW-UHFFFAOYSA-N
• SMILES: CNCC(c1ccc(OC)cc1)C1(O)CCCCC1