2-Linoleoyl-rac-glycerol

CAS: 3443-82-1

Ref. 3D-FL24902

Product Information

• Name: 2-Linoleoyl-rac-glycerol
• Synonyms: (9Z,12Z)-9,12-Octadecadienoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester2-Linoleoylglycerol2-Monolinolein, 1,3-dihydroxypropan-2-yl (9Z,12Z)-octadeca-9,12-dienoate, 2-Glyceryl 9,12-octadecadienoate, 2-Linoleoylglycerol, 2-Monolinolein, 2-Monolinoleoylglycerol, 9,12-Octadecadienoic acid (9Z,12Z)-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, 9,12-Octadecadienoic acid (Z,Z)-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, 9,12-octadecadienoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (9Z,12Z)-, Glycerin monolinoleate, Glycerol monolinoleate, Linolein, 2-mono-, β-Monolinolein

Description

2-Linoleoyl-rac-glycerol (2LAG) is a diacylglycerol that is produced from the hydrolysis of linoleic acid by the enzyme linoleic acid lipase. 2LAG activates cannabinoid receptors and has been shown to have anti-inflammatory, antibacterial, antioxidant, and antidiabetic activities. It also reduces body mass index in mice by decreasing food intake and increasing energy expenditure. 2LAG binds to cannabinoid receptors in the brain and peripheral tissues, where it inhibits fatty acid amide hydrolase activity, leading to an increase in endocannabinoid levels. This causes a decrease in appetite and weight gain. In addition, 2LAG has been shown to have radical scavenging effects against free radicals generated during lipid peroxidation. However, this compound may not be appropriate for use by women or people with high cholesterol levels.
2LAG is a precursor for arachidonic acid (AA), which

• Brand: Biosynth

Chemical properties

• Molecular weight: 354.52 g/mol
• Formula: C₂₁H₃₈O₄
• Purity: Min. 95%
• InChI: InChI=1S/C21H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h6-7,9-10,20,22-23H,2-5,8,11-19H2,1H3/b7-6-,10-9-
• InChI key: InChIKey=IEPGNWMPIFDNSD-HZJYTTRNSA-N
• SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(CO)CO