Loprinone hydrochloride

CAS: 119615-63-3

Ref. 3D-FL24930

Product Information

• Name: Loprinone hydrochloride
• Synonyms: 1,2-Dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochlorideOlprinone hydrochlorideCoretec, 1,2-Dihydro-5-imidazo[1,2-α]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride, 2-Hydroxy-5-(imidazo[1,2-a]pyridin-6-yl)-6-methylnicotinonitrile hydrochloride, 3-Pyridinecarbonitrile, 1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-, hydrochloride (1:1), 3-Pyridinecarbonitrile, 1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-, monohydrochloride, 3-Pyridinecarbonitrile,1,2-Dihydro-5-(Imidazo(1,2-A)Pyridin-6-Yl)-6-Methyl-2-O, Coretec, E 1020, E1020, Imidazo[1,2-a]pyridine, 3-pyridinecarbonitrile deriv., Loprinone hydrochloride, 1,2-Dihydro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride, Olprinone Hcl, Xo-,Monohydrochloride,Monohydrate

Description

Loprinone hydrochloride is an experimental drug that is being studied for its potential to treat congestive heart failure. It decreases the levels of cAMP, which are involved in a number of cellular processes, including the activation of signaling pathways and cardiac effects. The low-dose group showed significant improvements in their heart function compared to the control group. Loprinone hydrochloride has been shown to bind to a specific response element on DNA called the nuclear factor kappa B (NF-κB) response element and inhibit its transcriptional activity. Loprinone hydrochloride also inhibits IL-10, an anti-inflammatory cytokine that can cause myocardial infarction or other cardiovascular complications. Loprinone hydrochloride is not active against bowel disease, but it has been shown to be useful in treating glucose injection and diaphragmatic contractions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 286.72 g/mol
• Formula: C₁₄H₁₁ClN₄O
• Purity: Min. 98 Area-%