Z-Leu-Leu-OH

CAS: 7801-71-0

Ref. 3D-FL48226

Product Information

• Name: Z-Leu-Leu-OH
• Synonyms: Z-L-leucyl-L-leucineN-Carbobenzoxy-L-leucyl-L-leucine, <span class="text-smallcaps">L</smallcap>-Leucine, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-leucyl-, <span class="text-smallcaps">L</smallcap>-Leucine, N-[N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-leucyl]-, Benzyloxycarbonyl-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucine, Carbobenzoxy-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucine, Leucine, N-(N-carboxy-<span class="text-smallcaps">L</smallcap>-leucyl)-, N-benzyl ester, <smallcap>L</span>-, N-(N-(Benzyloxycarbonyl)-L-leucyl)-L-leucine, N-Carbobenzoxy-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucine, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucine, N-[(benzyloxy)carbonyl]leucylleucine, NSC 335978, N-Carbobenzoxy-L-leucyl-L-leucine, L-Leucine, N-[(phenylmethoxy)carbonyl]-L-leucyl-, L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-leucyl]-, Leucine, N-(N-carboxy-L-leucyl)-, N-benzyl ester, L-, N-[(Phenylmethoxy)carbonyl]-L-leucyl-L-leucine

Description

Z-Leu-Leu-OH is an irreversible, allosteric inhibitor of the cysteine proteinase enzyme. It binds to the active site of this enzyme and prevents its catalytic activity. Z-LEU-LEU-OH has been shown to inhibit the activation of inactive enzymes by calcium ions, as well as to bind to and inactivate activated enzymes. This compound also prevents peptidyl hydrolysis by cysteine proteinase, which is involved in the degradation of proteins and peptides. The inhibition of this enzyme may be useful for the treatment of ischaemic conditions such as stroke or myocardial infarction.

• Brand: Biosynth

Chemical properties

• Molecular weight: 378.46 g/mol
• Formula: C₂₀H₃₀N₂O₅
• Purity: Min. 95%