Leu-Leu-Leu-OH

CAS: 10329-75-6

Ref. 3D-FL49327

Product Information

• Name: Leu-Leu-Leu-OH
• Synonyms: L-Leucyl-L-leucyl-L-leucine, 135: PN: WO2009132287 SEQID: 171 claimed protein, 7: PN: US20160367463 SEQID: 8 claimed protein, 7: PN: WO2016204841 SEQID: 8 claimed protein, 8: PN: WO2020142103 SEQID: 8 claimed protein, <span class="text-smallcaps">L</smallcap>-Leucine, <smallcap>L</smallcap>-leucyl-<smallcap>L</span>-leucyl-, <span class="text-smallcaps">L</smallcap>-Leucine, N-(N-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-leucyl)-, <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-leucine, L-Leucy-L-Leucyl-L-Leucine, L-leucyl-L-leucyl-L-leucine, Leucine, N-(N-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</smallcap>-leucyl)-, <smallcap>L</span>-, Leucine, N-(N-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucyl)-, Leucylleucylleucine, Trileucine
• CAS: 10329-75-6

Description

Leu-Leu-Leu-OH is a pentapeptide that is used in cancer treatment to inhibit the growth of cancer cells. It prevents the production of proteins and, as a result, cell division. Leu-Leu-Leu-OH has been shown to be effective against tumor cells with an antibody that binds to the surface of cells. The monoclonal antibody is taken up by the cancer cells through receptor mediated endocytosis, which leads to inhibition of protein synthesis and cell death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 357.49 g/mol
• Formula: C₁₈H₃₅N₃O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)/t13-,14-,15-/m0/s1
• InChI key: InChIKey=DNDWZFHLZVYOGF-KKUMJFAQSA-N
• SMILES: CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O