Methyl 3-hydroxythiophene-2-carboxylate
CAS: 5118-06-9
Ref. 3D-FM02768
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued |
Product Information
Name:
Methyl 3-hydroxythiophene-2-carboxylate
Synonyms:
- 2-[hydroxy(methoxy)methylidene]thiophen-3(2H)-one
- (2E)-2-[hydroxy(methoxy)methylidene]thiophen-3(2H)-one
- Methyl-3-hydroxy-2-thiophene carboxylate
Description:
Methyl 3-hydroxythiophene-2-carboxylate is an organic compound consisting of a methyl group attached to a thiophene ring. It is a precursor to the drug amiloride, which is used to treat hypertension and edema. The compound can be formed by the reaction of hydrogen chloride with an alcohol in alkaline conditions. It can also be synthesized from 3-chlorothiophene-2-carboxylic acid and methanol in dilute hydrochloric acid. In addition, it can be prepared by chlorination of methyltetrahydrothiophene-2-carboxylic acid in the presence of copper(II) oxide as a catalyst. The compound has been decarboxylated at 200°C and then reacted with chloroform under refluxing conditions to produce amiloride.
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
158.18 g/mol
Formula:
C6H6O3S
Purity:
Min. 95%
InChI:
InChI=1S/C6H6O3S/c1-9-6(8)5-4(7)2-3-10-5/h2-3,7H,1H3
InChI key:
InChIKey=SEMVRXMFCHXUMD-UHFFFAOYSA-N
SMILES:
COC(=O)c1sccc1O
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