Product correctly added to cart.

discount label
Minalrestat
View 3D

Biosynth logo

Minalrestat

CAS: 129688-50-2

Ref. 3D-FM103259

Undefined sizeTo inquire
Estimated delivery in United States, on Monday 16 Dec 2024

Product Information

Name:
Minalrestat
Synonyms:
  • 2-(4-Bromo-2-fluorobenzyl)-6-fluorospiro(isoquinoline-4(1H),3'-pyrrolidine)-1,2',3,5'(2H)-tetrone
  • 2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone
  • 2-[(4-Bromo-2-fluorophenyl)methyl]-6-fluorospiro[isoquinoline-4(1H),3′-pyrrolidine]-1,2′,3,5′(2H)-tetrone
  • Ari 509
  • Minalrestat [USAN:INN]
  • Spiro(isoquinoline-4(1H),3'-pyrrolidine)-1,2',3,5'(2H)-tetrone, 2-((4-bromo-2-fluorophenyl)-methyl)-6-fluoro-
  • Spiro[isoquinoline-4(1H),3′-pyrrolidine]-1,2′,3,5′(2H)-tetrone, 2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-
  • Unii-G44Pe6Qb31
  • Way-Ari-509
Description:

Minalrestat is a drug that has been approved for use in humans to treat type 2 diabetes. It is an inhibitor of hormone-sensitive lipase and has shown a hypoglycemic effect in diabetic animals. Minalrestat binds to the protein target, which is essential for the regulation of blood glucose levels. The drug has been shown to be effective against diabetic neuropathy and congestive heart disease. Minalrestat is not metabolized by the liver or kidneys, which allows it to be used safely in patients with renal or hepatic dysfunction, as well as those who are pregnant or breastfeeding. Minalrestat can also be administered orally, intravenously, or subcutaneously and its pharmacokinetic properties have been studied extensively in both humans and animals.
Minalrestat increases insulin sensitivity by binding to the insulin receptor on cells without activating it directly. It also inhibits glucose uptake into cells by blocking the transporter GLUT4 at physiological concentrations. This binding prevents insulin from being

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
449.2 g/mol
Formula:
C19H11BrF2N2O4
Purity:
Min. 95%
InChI:
InChI=1S/C19H11BrF2N2O4/c20-10-2-1-9(14(22)5-10)8-24-16(26)12-4-3-11(21)6-13(12)19(18(24)28)7-15(25)23-17(19)27/h1-6H,7-8H2,(H,23,25,27)
InChI key:
InChIKey=BMHZAHGTGIZZCT-UHFFFAOYSA-N
SMILES:
O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1ccc(F)cc12
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: 3D-FM103259 Minalrestat

Please use instead the cart to request a quotation or an order

If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.

* Mandatory fields.
Welcome to CymitQuimica!We use cookies to enhance your visit. We do not include advertising.

Please see our Cookies Policy for more details or adjust your preferences in "Settings".