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N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]…
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N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide

CAS: 717906-29-1

Ref. 3D-FM103640

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Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide
Synonyms:
  • N-Methyl-N-{2-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl}amino)methyl]phenyl}methanesulfonamide
Description:

N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide is a kinase inhibitor that has been shown to inhibit the activity of the protein kinases CDK4 and CDK6. This drug blocks the phosphorylation of the cyclins and causes cell cycle arrest. NMEPMP binds to the ATP binding site of these kinases and prevents ATP from binding, which leads to inhibition of downstream events such as transcription, translation, and mitosis. This drug has been shown to be effective in preclinical models for cancer and pancreatitis.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
506.5 g/mol
Formula:
C22H21F3N6O3S
Purity:
Min. 95%
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
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Packing Group:
LQ:

Technical inquiry about: 3D-FM103640 N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide

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