4-Maleimidobutyric acid

CAS: 57078-98-5

Ref. 3D-FM10662

Product Information

• Name: 4-Maleimidobutyric acid
• Synonyms: 1H-Pyrrole-1-butanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-butanoic acid, 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid, 4-Maleimidobutanoic acid, N-(3-Carboxypropyl)maleimide, γ-Maleimidobutyric acid, ω-Maleimidobutyric acid

Description

4-Maleimidobutyric acid is a molecule that is used for the immobilization of peptides and proteins. It has been shown to bind to lysine residues on the surface of epidermal growth factor, which may be due to its ability to form covalent bonds with amino groups. This binding prevents the protein from interacting with cells in culture. 4-Maleimidobutyric acid also inhibits bacterial growth, including activity against Staphylococcus aureus, Bacillus anthracis, Mycobacterium tuberculosis, and Pseudomonas aeruginosa. 4-Maleimidobutyric acid has been shown to inhibit cancer cell proliferation in a Ca2+-dependent manner. It may also be effective as an antimicrobial agent due to its ability to disrupt proton gradients and acidic environments found in bacteria.

• Brand: Biosynth

Chemical properties

• Molecular weight: 183.16 g/mol
• Formula: C₈H₉NO₄
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C8H9NO4/c10-6-3-4-7(11)9(6)5-1-2-8(12)13/h3-4H,1-2,5H2,(H,12,13)
• InChI key: InChIKey=NCPQROHLJFARLL-UHFFFAOYSA-N
• SMILES: O=C(O)CCCN1C(=O)C=CC1=O