N-(4-Methoxybenzyl)pyridin-2-amine

CAS: 52818-63-0

Ref. 3D-FM117196

Product Information

• Name: N-(4-Methoxybenzyl)pyridin-2-amine
• Synonyms: 2-(p-Methoxybenzylamino)pyridine, 2-Pyridinamine, N-[(4-methoxyphenyl)methyl]-, 2-[(4-Methoxybenzyl)Amino]Pyridinium, N-(4-methoxybenzyl)pyridin-2-amine, N-(4-methoxyphenyl)pyridin-2-amine, NSC 124138, N[(4-Methoxyphenyl)methyl]-2-pyridinamine, P-Anisyl(2-Pyridyl)Amine, Pyridine, 2-(p-methoxybenzylamino)-, Skf 47437

Description

N-(4-Methoxybenzyl)pyridin-2-amine is a quaternary ammonium salt. It has been shown to be an antagonist of the histamine H1 receptor in vitro and in vivo. N-(4-Methoxybenzyl)pyridin-2-amine inhibits histamine release from rat peritoneal mast cells. The compound also displays antiproliferative activity against human glioblastoma cells, with IC50 values of 10 µM for U87 and 13 µM for U251. In addition, the compound is antagonistic toward exocyclic amines such as phenacyl. The nitrogen atom in this molecule is responsible for its fluorescent properties, which may be useful for detecting it in vivo or in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 214.26 g/mol
• Formula: C₁₃H₁₄N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C13H14N2O/c1-16-12-7-5-11(6-8-12)10-15-13-4-2-3-9-14-13/h2-9H,10H2,1H3,(H,14,15)
• InChI key: InChIKey=SMJGJENXFSWIMQ-UHFFFAOYSA-N
• SMILES: COc1ccc(CNc2ccccn2)cc1