1-Methylquinazoline-2,4(1H,3H)-dione

CAS: 604-50-2

Ref. 3D-FM127997

Product Information

• Name: 1-Methylquinazoline-2,4(1H,3H)-dione
• Synonyms: 2,4(1H,3H)-quinazolinedione, 1-methyl-, 1,2,3,4-Tetrahydro-1-methyl-2,4-dioxoquinazoline, 1-Methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione, 1-Methyl-1H-quinazoline-2,4-dione, 1-Methyl-2,4(1H,3H)-quinazolinedione, 1-Methyl-2,4-quinazolinedione, 2,4(1H,3H)-quinazolinedione, 1-methyl-, Glycosmicine, NSC 401254

Description

1-Methylquinazoline-2,4(1H,3H)-dione is a precursor of β-carboline alkaloids. It is a metabolite of tryptophan and interacts with the enzyme synthase to produce β-carbolines. 1-Methylquinazoline-2,4(1H,3H)-dione can be detected in bovine serum and urine by ultraviolet spectroscopy. The fluorescence of 1-methylquinazoline-2,4(1H,3H)-dione has been shown to increase when it binds to amines. In vitro experiments have shown that 1-methylquinazoline-2,4(1H,3H)-dione may have synergistic effects with quinazolone against malaria parasites and antifungal activity against Candida albicans. The constant for this compound is 343.5nmol/L at pH 7.0 and 298

• Brand: Biosynth

Chemical properties

• Molecular weight: 176.17 g/mol
• Formula: C₉H₈N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C9H8N2O2/c1-11-7-5-3-2-4-6(7)8(12)10-9(11)13/h2-5H,1H3,(H,10,12,13)
• InChI key: InChIKey=RWFOOMQYIRITHL-UHFFFAOYSA-N
• SMILES: Cn1c(=O)[nH]c(=O)c2ccccc21