[5-(4-Methylpiperazin-1-yl)-2-nitrophenyl]amine

CAS: 23491-48-7

Ref. 3D-FM132558

Product Information

• Name: [5-(4-Methylpiperazin-1-yl)-2-nitrophenyl]amine
• Synonyms: 5-(4-methylpiperazin-1-yl)-2-nitroanilinebenzenamine, 5-(4-methyl-1-piperazinyl)-2-nitro-, 1-(3-Amino-4-nitrophenyl)-4-methylpiperazine, 5-(4-Methylpiperazino)-2-Nitroaniline, 4-(3-Amino-4-Nitrophenyl)-1-Methylpiperazin-1-Ium

Description

5-(4-Methylpiperazin-1-yl)-2-nitrophenyl]amine is a potential agent for the treatment of benzene poisoning. It has been shown to be an irreversible inhibitor of the enzyme dihydrofolate reductase, which plays a role in the synthesis of DNA and proteins. 5-(4-Methylpiperazin-1-yl)-2-nitrophenyl]amine reversibly inhibits methylamine dehydrogenase (EC 1.4.1.3) with a Ki value of 0.8 mM and also inhibits pyridoxal phosphate dependent aminotransferases, including alanine aminotransferase (EC 2.6.1.2), aspartate aminotransferase (EC 2.6.1.1), and glycine aminotransferase (EC 2.6.1.19). The inhibition of these enzymes

• Brand: Biosynth

Chemical properties

• Molecular weight: 236.27 g/mol
• Formula: C₁₁H₁₆N₄O₂
• Purity: Min. 95%