5-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid

CAS: 3993-73-5

Ref. 3D-FM132566

Product Information

• Name: 5-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
• Synonyms: 4-pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-5-methyl-2,6-dioxo-, 1,2,3,6-Tetrahydro-5-methyl-2,6-dioxo-4-pyrimidinecarboxylic acid, 2,6-Dihydroxy-5-methyl-4-carboxy pyrimidine, 2,6-Dihydroxy-5-methyl-4-pyrimidinecarboxylic acid, 2,6-Dihydroxy-5-methylpyrimidine-4-carboxylic acid, 2-Hydroxy-5-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-5-methyl-2,6-dioxo-, 4-Pyrimidinecarboxylic acid, 2,6-dihydroxy-5-methyl-, 5-Methyl-2,6-Dioxo-1,2,3,6-Tetrahydropyrimidine-4-Carboxylic Acid, 5-Methylorotic acid, 6-Thyminecarboxylic acid, Methylorotic acid, NSC 667244, Nsc 52390, Nsc 98530, Orotic acid, 5-methyl-, 1,2,3,6-Tetrahydro-5-methyl-2,6-dioxopyrimidine-4-carboxylic acid

Description

5-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid is a potent inhibitor of copper enzymes such as activated copper salt and expressed copper protein. It binds to the anionic site of the enzyme and blocks the binding of substrate. The benzyl group and chlorine are two important functional groups in this compound that can bind to other ligands. 5-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid has been shown to inhibit the activity of carbonyl ligands such as thiomorpholine and methylamine. This drug also has an active methylene group that can bind to orotic acid.

• Brand: Biosynth

Chemical properties

• Molecular weight: 170.12 g/mol
• Formula: C₆H₆N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C6H6N2O4/c1-2-3(5(10)11)7-6(12)8-4(2)9/h1H3,(H,10,11)(H2,7,8,9,12)
• InChI key: InChIKey=UQBMFARVSOQVQE-UHFFFAOYSA-N
• SMILES: Cc1c(C(=O)O)[nH]c(=O)[nH]c1=O