N-Methylprolinamide hydrochloride

CAS: 137693-34-6

Ref. 3D-FM134433

Product Information

• Name: N-Methylprolinamide hydrochloride
• Synonyms: 2-pyrrolidinecarboxamide, N-methyl-, hydrochloride

Description

The present invention provides a method for preparing N-methylprolinamide hydrochloride. The method is carried out in a single step by reacting 3-phenyl-1,2,4-triazole with an aryl halide in the presence of copper iodide and a base. The reaction proceeds via the cross-coupling of an aryl halide with an amine to form an imine intermediate that undergoes reductive elimination to produce the desired product. This process is efficient and has been shown to be scalable to large scale reactions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 128.17 g/mol
• Formula: C₆H₁₂N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C6H12N2O/c1-7-6(9)5-3-2-4-8-5/h5,8H,2-4H2,1H3,(H,7,9)
• InChI key: InChIKey=URHXQSTYLJNJMT-UHFFFAOYSA-N
• SMILES: CNC(=O)C1CCCN1