Methyl 5-methylpicolinate

CAS: 29681-38-7

Ref. 3D-FM140124

Product Information

• Name: Methyl 5-methylpicolinate
• Synonyms: 2-Pyridinecarboxylic Acid, 5-Methyl-, Methyl Ester

Description

Methyl 5-methylpicolinate is a pyridine that can be used in the preparation of cycloadducts, annulations, and cycloadditions. It can be prepared by reacting p-toluenesulfonyl chloride with methyl 3-hydroxybenzoate and methyl 4-chlorobenzoate. This reaction forms a diene that can react with various dienophiles to form different products. The regiocontrolled synthesis of methyl 5-methylpicolinate has been achieved by carrying out the Diels-Alder reaction between pyridines and oxides or chlorides.
Methyl 5-methylpicolinate can be used as a precursor for the synthesis of both 1,4-dimethylpiperazine and 2,5-dimethylpiperazine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 151.16 g/mol
• Formula: C₈H₉NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H9NO2/c1-6-3-4-7(9-5-6)8(10)11-2/h3-5H,1-2H3
• InChI key: InChIKey=GLXLMXAFURBIEZ-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(C)cn1