Methyl 2-(2-(benzyloxycarbonylamino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate

CAS: 519032-08-7

Ref. 3D-FM140381

Product Information

• Name: Methyl 2-(2-(benzyloxycarbonylamino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate
• Synonyms: 1,6-dihydro-5-hydroxy-2-[1-methyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]-6-oxo-4-Pyrimidinecarboxylie acid methyl ester, 2-(1-Benzyloxycarbonylamino-1-methylethyl)-5,6-dihydroxypyrimidine-4-carboxylic acid methyl ester, 4-Pyrimidinecarboxylic Acid, 1,6-Dihydro-5-Hydroxy-2-[1-Methyl-1-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]-6-Oxo-, Methyl Ester, Methyl 1,6-dihydro-5-hydroxy-2-[1-methyl-1-[[(phenylmethoxy)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxylate, Methyl 2-[1-[(benzyloxy)carbonyl]amino]-1-(1-methylethyl)-5,6-dihydroxypyrimidine-4-carboxylate, Methyl2-(2-(benzyloxycarbonylamino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate
• CAS: 519032-08-7

Description

Methyl 2-(2-(benzyloxycarbonylamino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate is a dihedral molecule that has a crystal structure stabilized by hydrogen bonds. It has been shown to be active against methicillin resistant Staphylococcus aureus and Mycobacterium tuberculosis with good in vitro activity. Methyl 2-(2-(benzyloxycarbonylamino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine -4 carboxylate is a prodrug that is hydrolyzed in vivo to its active form, the cytotoxic methyl 5'-hydroxy 6'-oxopyrimidin (MP).

• Brand: Biosynth

Chemical properties

• Molecular weight: 361.35 g/mol
• Formula: C₁₇H₁₉N₃O₆
• Purity: Min. 95%
• InChI: InChI=1S/C17H19N3O6/c1-17(2,20-16(24)26-9-10-7-5-4-6-8-10)15-18-11(14(23)25-3)12(21)13(22)19-15/h4-8,21H,9H2,1-3H3,(H,20,24)(H,18,19,22)
• InChI key: InChIKey=NIVUTAZNLHLBAN-UHFFFAOYSA-N
• SMILES: COC(=O)c1nc(C(C)(C)NC(=O)OCc2ccccc2)[nH]c(=O)c1O