2-Methyl-5-nitrobenzenesulfonamide
CAS: 6269-91-6
Ref. 3D-FM143864
| 25g | Discontinued | ||
| 50g | Discontinued | ||
| 100g | Discontinued | ||
| 250g | Discontinued | ||
| 500g | Discontinued |
Product Information
Name:
2-Methyl-5-nitrobenzenesulfonamide
Synonyms:
- 2-Methyl-5-nitrobenzenesulphonamide
- 2-Methyl-5-Nitrobenzene-1-Sulfonamide
- 2-Methyl-5-nitrobenzene sulphonamide
Description:
2-Methyl-5-nitrobenzenesulfonamide is a synthetic nitrosated hydroxamic acid that inhibits the histone deacetylase enzyme. This leads to an increase in gene transcription and protein synthesis. 2-Methyl-5-nitrobenzenesulfonamide has been shown to be highly potent against various cancer cell lines, including breast, ovarian, and prostate cancers. It is also used as a lead compound in the development of pazopanib, which is a drug for the treatment of advanced renal cell carcinoma. Pazopanib is metabolized by CYP3A4 enzymes to form 2-methyl-5-nitrobenzenesulfonamide. The impurities found in this drug are not toxic and do not contribute to its antitumor activity.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
216.22 g/mol
Formula:
C7H8N2O4S
Purity:
Min. 95%
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