Methyl 6-bromo-1H-indazole-4-carboxylate

CAS: 885518-49-0

Ref. 3D-FM143978

Product Information

• Name: Methyl 6-bromo-1H-indazole-4-carboxylate
• Synonyms: 6-bromo-4-Indazolecarboxylic acid methyl ester, methyl 6-bromo-1H-indazole-4-carboxylate

Description

Methyl 6-bromo-1H-indazole-4-carboxylate is an amide that inhibits the production of cytokines and angiogenesis, thereby inhibiting tumor growth. It has been shown to have antiangiogenic activity in animal models and inhibited tumor growth in human cancer cells. Methyl 6-bromo-1H-indazole-4-carboxylate also showed a radical scavenging activity, which may be due to its ability to neutralize reactive oxygen species (ROS). It has been shown to have antioxidant effects by protecting cells from oxidative damage. Methyl 6-bromo-1H-indazole-4-carboxylate is synthesized through a radical coupling reaction with methyl acrylate and indazole. The structure of this compound was elucidated using X ray crystallography.

• Brand: Biosynth

Chemical properties

• Molecular weight: 255.07 g/mol
• Formula: C₉H₇BrN₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C9H7BrN2O2/c1-14-9(13)6-2-5(10)3-8-7(6)4-11-12-8/h2-4H,1H3,(H,11,12)
• InChI key: InChIKey=FEPRHRPOKPTRQZ-UHFFFAOYSA-N
• SMILES: COC(=O)c1cc(Br)cc2[nH]ncc12