4-(4-Methylpiperazino)-1,2-benzenediamine

CAS: 54998-08-2

Ref. 3D-FM147511

Product Information

• Name: 4-(4-Methylpiperazino)-1,2-benzenediamine
• Synonyms: 1,2-Benzenediamine, 4-(4-Methyl-1-Piperazinyl)-, 4-(4-Methylpiperazin-1-yl)benzene-1,2-diamine, 4-(4-Methylpiperazin-1-yl)benzol-1,2-diamin
• CAS: 54998-08-2

Description

4-(4-Methylpiperazino)-1,2-benzenediamine (4MPBD) is a small molecule that binds to the telomerase enzyme and inhibits its activity. Telomerase is an enzyme that maintains telomeres by adding nucleotides to the end of dna strands. 4MPBD has been shown to inhibit telomerase activity in vitro and in vivo, and it has been found to induce apoptosis in cancer cells. This compound also stabilizes telomeres and causes a shift in the equilibrium between short and long telomeres. The inhibition of telomerase by 4MPBD may lead to an increased risk of cancer progression and death, as well as an increase in susceptibility to infection due to shortened dna strands.

• Brand: Biosynth

Chemical properties

• Molecular weight: 206.29 g/mol
• Formula: C₁₁H₁₈N₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H18N4/c1-14-4-6-15(7-5-14)9-2-3-10(12)11(13)8-9/h2-3,8H,4-7,12-13H2,1H3
• InChI key: InChIKey=RTDKAEOVZXYWJW-UHFFFAOYSA-N
• SMILES: CN1CCN(c2ccc(N)c(N)c2)CC1