Product Information
- (2-Methyl-5-nitrophenyl)guanidine
- 1-(2-Methyl-5-nitrophenyl)guanidine
- 2-(2-Methyl-5-Nitrophenyl)Guanidine
- N-(2-Methyl-5-nitrophenyl)guanidine
- guanidine, N-(2-methyl-5-nitrophenyl)-
2-Methyl-5-nitrophenylguanidine is an amide with the functional group of an amine. It has a molecular weight of 178.2 g/mol and a melting point of 181 °C. 2-Methyl-5-nitrophenylguanidine can be synthesized by reacting 3-acetylpyridine with hydrochloric acid and nitric acid in an organic solvent, such as chloroform or ether, at a temperature range of 25°C to 100°C. This compound has been found to be one of the impurities in the synthesis of imatinib, which can be removed through recrystallization or fractional distillation. The chloride impurity can also be removed using hydrolysis with sodium hydroxide followed by acidification, which removes the chlorides and nitro groups from the molecule. 2-Methyl-5-nitrophenylguanidine is used for the synthesis of
Chemical properties
Technical inquiry about: 3D-FM148503 2-Methyl-5-nitrophenylguanidine
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