4-Methyl-1,3-thiazole-2(3H)-thione

CAS: 5685-06-3

Ref. 3D-FM148856

Product Information

• Name: 4-Methyl-1,3-thiazole-2(3H)-thione
• Synonyms: 2(3H)-Thiazolethione, 4-methyl-, 2-Mercapto-4-methyl-1,3-thiazole, 2-Mercapto-4-methylthiazole, 2-Thiazolethiol, 4-methyl-, 4-Methyl-2(3H)-thiazolethione, 4-Methyl-2-mercaptothiazole, 4-Methyl-2-thiazolethiol, 4-Methyl-4-thiazoline-2-thione, 4-Methylthiazole-2-thione, 4-Methylthiazoline-2-thione, 4-Thiazoline-2-thione, 4-methyl-, 4-methyl-1,3-thiazole-2(3H)-thione, Nsc 40808
• CAS: 5685-06-3

Description

4-Methyl-1,3-thiazole-2(3H)-thione is a potent inhibitor of mammalian cell growth. It has been shown to be effective against bacterial cultures, such as Staphylococcus aureus, and in vitro models of diabetic patients. 4-Methyl-1,3-thiazole-2(3H)-thione inhibits the synthesis of fatty acids by blocking the thiolation of cysteine residues. It is synthesized from 2,4-dimethylthiazolium chloride and 4-(methylsulfanyl)phenylamine. The inhibition potency values for 4-methyl-1,3-thiazole-2(3H)-thione are IC50 = 0.07 mM and IC50 = 0.03 mM on human fibroblast cells and rat liver microsomes respectively.

• Brand: Biosynth

Chemical properties

• Molecular weight: 131.22 g/mol
• Formula: C₄H₅NS₂
• Purity: Min. 95%