4-Methylnicotinamide

CAS: 7250-52-4

Ref. 3D-FM148886

Product Information

• Name: 4-Methylnicotinamide
• Synonyms: 3-Pyridinecarboxamide, 4-methyl-, 4-Methyl-3-pyridinecarboxamide, 4-Methylpyridine-3-Carboxamide, NSC 131712, NSC 30041, Nicotinamide, 4-methyl-

Description

4-Methylnicotinamide is a compound that has been shown to be able to alleviate the symptoms of Parkinson's disease. It is an inhibitor of glyceraldehyde 3-phosphate dehydrogenase, which is an enzyme involved in the metabolism of glucose. 4-Methylnicotinamide acts by inhibiting the activity of this enzyme and thus preventing the production of NAD+, which is essential for cellular energy production. This inhibition may be due to its ability to act as a methyltransferase or dehydrogenase. The inhibitory effect on this enzyme leads to decreased levels of NAD+ and increased levels of glyceraldehyde 3-phosphate, leading to an accumulation of 4-methoxybenzaldehyde, which can accept amines.

• Brand: Biosynth

Chemical properties

• Molecular weight: 136.15 g/mol
• Formula: C₇H₈N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C7H8N2O/c1-5-2-3-9-4-6(5)7(8)10/h2-4H,1H3,(H2,8,10)
• InChI key: InChIKey=SXKLOQCGXUTBNP-UHFFFAOYSA-N
• SMILES: Cc1ccncc1C(N)=O