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2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

CAS: 445264-61-9

Ref. 3D-FM153016

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Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Synonyms:
  • (2-Methoxypyridin-5-yl)boronic acid pinacol ester
  • 2-(6-Methoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin
  • 2-Methoxy-5-pyridineboronic acid pinacol ester
  • 2-Methoxyl-5-Pyridineboronic Acid Pinacol Ester
  • 2-Methoxypyridine-5-boronic acid pinacol ester
  • Pyridine, 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
Description:

2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (MTDPB) is a ligand that has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. MTDPB binds to the ATP site on the enzyme mTORC2 and inhibits cellular proliferation by blocking mTORC2 activation. This inhibition leads to a reduction in cell number and size. Additionally, MTDPB has been shown to have anti-inflammatory effects by inhibiting the production of prostaglandin E2 and cytokines such as IL6 and TNFα. MTDPB may be used for the treatment of cancers such as colon cancer or breast cancer.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
235.09 g/mol
Formula:
C12H18BNO3
Purity:
Min. 95%
InChI:
InChI=1S/C12H18BNO3/c1-11(2)12(3,4)17-13(16-11)9-6-7-10(15-5)14-8-9/h6-8H,1-5H3
InChI key:
InChIKey=QOGNDJLSYMJGPP-UHFFFAOYSA-N
SMILES:
COc1ccc(B2OC(C)(C)C(C)(C)O2)cn1
MDL:
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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