(±)-3-Methyl-2-oxovaleric acid

CAS: 1460-34-0

Ref. 3D-FM157432

Product Information

• Name: (±)-3-Methyl-2-oxovaleric acid
• Synonyms: 2-Oxo-3(RS)-methylvaleric acid, 2-Oxo-3-methyl-n-valeric acid, 2-Oxo-3-methylpentanoic acid, 2-Oxo-3-methylvaleric acid, 2-Oxoisoleucine, 3-Ethyl-3-methylpyruvic acid, 3-Methyl-2-ketovaleric acid, 3-Methyl-2-oxopentanoic acid, 3-Methyl-2-oxovaleric acid, <span class="text-smallcaps">DL</span>-3-Ethyl-3-methylpyruvic acid, <span class="text-smallcaps">DL</span>-3-Methyl-2-oxopentanoate, <span class="text-smallcaps">DL</span>-3-Methyl-2-oxopentanoic acid, Pentanoic acid, 3-methyl-2-oxo-, Sodium 3-Methyl-2-Oxopentanoate, Valeric acid, 3-methyl-2-oxo-, alpha-Keto-beta-methylvaleric acid, α-Keto-β-methylvaleric acid, α-Oxo-β-methyl-n-valeric acid, α-Oxo-β-methylvaleric acid, α-keto-β-Methyl-n-valeric acid
• CAS: 1460-34-0

Description

(±)-3-Methyl-2-oxovaleric acid is a fatty acid that is found in the mitochondria of liver cells and other tissues. It is an intermediate in the citric acid cycle and can be converted into acetyl-CoA, which is used for energy production. (±)-3-Methyl-2-oxovaleric acid has been shown to cause necrotic cell death when it binds to the mitochondrial membrane potential and causes a loss of ATP production. This results in a lack of energy for the cell, leading to cell death. (±)-3-Methyl-2-oxovaleric acid has also been shown to inhibit protein synthesis by decreasing uptake and increasing creatine kinase activity. This inhibition leads to decreased body formation and tissue culture growth in vitro. In vivo, (±)-3-Methyl-2-oxovaleric acid causes primary sclerosing cholangitis, a disease characterized by inflammation of bile ducts that

• Brand: Biosynth

Chemical properties

• Molecular weight: 130.14 g/mol
• Formula: C₆H₁₀O₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C6H10O3/c1-3-4(2)5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)
• InChI key: InChIKey=JVQYSWDUAOAHFM-UHFFFAOYSA-N
• SMILES: CCC(C)C(=O)C(=O)O