Mercaptosuccinic acid

CAS: 70-49-5

Ref. 3D-FM160137

Product Information

• Name: Mercaptosuccinic acid
• Synonyms: (2S)-2-sulfanylbutanedioic acid, 2-Mercaptobutanedioic acid, 2-Mercaptosuccinic acid, 2-Sulfanylbutanedioic acid, 2-Thiomalic acid, <span class="text-smallcaps">DL</span>-Mercaptosuccinic acid, <span class="text-smallcaps">DL</span>-Thiomalic acid, Acide mercaptosuccinique, Acido Mercaptosuccinico, Butanedioic acid, 2-mercapto-, Butanedioic acid, mercapto-, DL-Thiomalic acid, Mercaptobernsteinsaure, Mercaptobutanedioic acid, Mercaptobutanedoic acid, Monomercaptosuccinic acid, Nsc 7302, Succinic acid, mercapto-, Thioapfelsaeure, Thiomalic acid, α-Mercaptosuccinic acid

Description

Mercaptosuccinic acid is a chemical compound that has shown significant cytotoxicity in vitro. It is a fluorescence probe for the study of hydrogen peroxide, which reacts with the mercaptosuccinic acid to form an adduct that can be detected by fluorescence spectroscopy. Mercaptosuccinic acid also has a synergic effect with sodium citrate, which has been shown to inhibit hl-60 cells. The optimum concentration of mercaptosuccinic acid needed for cytotoxicity varies depending on the type of cell and can be determined using experimental results. The reaction mechanism of mercaptosuccinic acid is not well understood but it is thought to involve oxidation of p-hydroxybenzoic acid and ester linkages. Mercaptosuccinic acid also reduces mitochondrial membrane potential, which may contribute to its cytotoxic effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 150.15 g/mol
• Formula: C₄H₆O₄S
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C4H6O4S/c5-3(6)1-2(9)4(7)8/h2,9H,1H2,(H,5,6)(H,7,8)
• InChI key: InChIKey=NJRXVEJTAYWCQJ-UHFFFAOYSA-N
• SMILES: O=C(O)CC(S)C(=O)O