(2R,4S)-Methyl 4-hydroxypyrrolidine-2-carboxylate

CAS: 1499-56-5

Ref. 3D-FM162524

Product Information

• Name: (2R,4S)-Methyl 4-hydroxypyrrolidine-2-carboxylate
• Synonyms: (2S,4R)-4-Hydroxy-2-(methoxycarbonyl)pyrrolidine, (2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic acid methyl ester, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester, (2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate, (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester, <span class="text-smallcaps">L</span>-Hydroxyproline methyl ester, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, (4R)-, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, trans-, L-Proline, 4-Hydroxy-, Methyl Ester, (4R)-, Methyl (4R)-4-Hydroxy-L-Prolinate, Methyl 4-Hydroxy-L-Prolinate, Methyl(2S,4R)-4-Hydroxypyrrolidine-2-Carboxylate, Proline, 4-hydroxy-, methyl ester, <span class="text-smallcaps">L</span>-trans-, trans-3-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester, trans-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester

Description

(2R,4S)-Methyl 4-hydroxypyrrolidine-2-carboxylate is a potent matrix metalloproteinase inhibitor that has been shown to inhibit the activity of the metalloproteinases in vitro and in vivo. It inhibits the polymerization of pro-matrix metalloproteinase (pro-MMP) by binding to the active site of pro-MMP and preventing it from degrading the tissue. It also inhibits MMPs that are involved in tumor invasion and metastasis, such as MMP-2 and MMP-9. (2R,4S)-Methyl 4-hydroxypyrrolidine-2-carboxylate has also been shown to be effective against cancer cells in vitro. The drug binds to DNA and RNA molecules, inhibiting their synthesis. This leads to cell death when there is insufficient energy production for maintenance of normal cell functions. The drug has also been shown to inhibit

• Brand: Biosynth

Chemical properties

• Molecular weight: 145.16 g/mol
• Formula: C₆H₁₁NO₃
• Purity: Min. 95%