5-Methylpyridine-3-carbohydrazide

CAS: 808127-97-1

Ref. 3D-FM166574

Product Information

• Name: 5-Methylpyridine-3-carbohydrazide

Description

5-Methylpyridine-3-carbohydrazide is an important chiral intermediate that is used in the synthesis of sulfonamides. The compound can be prepared by a process called the Corey-Chaykovsky reaction, which involves the addition of methyl acetoacetate to 3-hydroxybenzaldehyde. This process is a bottleneck in the synthesis of sulfonamides due to its lack of stereospecificity and high reactivity with water. It has been shown that 5-methylpyridine-3-carbohydrazide can be synthesized using a more effective process, such as one involving the use of sodium metal and methylformamide.

• Brand: Biosynth

Chemical properties

• Molecular weight: 151.17 g/mol
• Formula: C₇H₉N₃O
• Purity: Min. 95%
• InChI: InChI=1S/C7H9N3O/c1-5-2-6(4-9-3-5)7(11)10-8/h2-4H,8H2,1H3,(H,10,11)
• InChI key: InChIKey=NAVCFSQHLVLTQF-UHFFFAOYSA-N
• SMILES: Cc1cncc(C(=O)NN)c1