Mariptiline

CAS: 60070-14-6

Ref. 3D-FM170108

Product Information

• Name: Mariptiline
• Synonyms: 1a,10b-Dihydrodibenzo(a,e)cyclopropa(c)cyclohepten-6(1H)-one O-(2-aminoethyl)oxime, 2-[(1a,10b-dihydrodibenzo[a,e]cyclopropa[c][7]annulen-6(1H)-ylideneamino)oxy]ethanamine, Dibenzo[a,e]cyclopropa[c]cyclohepten-6(1H)-one, 1a,10b-dihydro-, O-(2-aminoethyl)oxime, Mariptilina, Mariptiline [INN], Mariptilinum, Unii-E27T357050

Description

Mariptiline is a monoamine oxidase inhibitor that can be used to inhibit the uptake of monoamines and may be useful in the treatment of cancer. It acts as a targetable uptake inhibitor by binding to the membrane transporter responsible for transporting amines into cells. The drug is insoluble and must be reconstituted with a diluent before use. Mariptiline can also be administered by iontophoresis, which delivers drugs through electric current. This method may be more effective than oral ingestion because it circumferentially delivers drugs to tumors. Mariptiline inhibits the activity of an enzyme called foxo1, which is involved in tumor development and progression, making it a possible therapeutic agent for treating cancer. Mariptiline also has been shown to inhibit α2-adrenergic receptors, which are implicated in the regulation of tumor growth and metastasis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 278.35 g/mol
• Formula: C₁₈H₁₈N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C18H18N2O/c19-9-10-21-20-18-14-7-3-1-5-12(14)16-11-17(16)13-6-2-4-8-15(13)18/h1-8,16-17H,9-11,19H2
• InChI key: InChIKey=ZJUNTBVPKYZTPD-UHFFFAOYSA-N
• SMILES: NCCON=C1c2ccccc2C2CC2c2ccccc21