4-(Maleimido)benzophenone

CAS: 92944-71-3

Ref. 3D-FM24976

Product Information

• Name: 4-(Maleimido)benzophenone
• Synonyms: 1-(4-Benzoylphenyl)-1H-pyrrole-2,5-dioneN-(4-Benzoylphenyl)maleimide, Benzophenone-4-maleimide, 1-(4-benzoylphenyl)-1H-pyrrole-2,5-dione
• CAS: 92944-71-3

Description

4-(Maleimido)benzophenone is a compound that has been used in cardiac research. It inhibits the activity of glutamate dehydrogenase, an enzyme that catalyzes the conversion of glutamate to alpha-ketoglutarate. This compound has been shown to cause subcellular changes such as filament formation, increased cytosolic calcium levels, and actin filament disruption. 4-(Maleimido)benzophenone also has been shown to inhibit both the cardiac L-type calcium channel and the sarcolemmal K+ channel in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 277.27 g/mol
• Formula: C₁₇H₁₁NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C17H11NO3/c19-15-10-11-16(20)18(15)14-8-6-13(7-9-14)17(21)12-4-2-1-3-5-12/h1-11H
• InChI key: InChIKey=OZIZEXQRIOURIJ-UHFFFAOYSA-N
• SMILES: O=C(c1ccccc1)c1ccc(N2C(=O)C=CC2=O)cc1