Melperone

CAS: 3575-80-2

Ref. 3D-FM25046

Product Information

• Name: Melperone
• Synonyms: 1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanoneMethylperoneFlubuperone, 1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone, 1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-, 4'-Fluor-4-(4-methylpiperidino)butyrophenon, 4'-Fluoro-4-(4-methylpiperidino)butyrophenone, 4-Fluoro-γ-(4-methylpiperidino)butyrophenone, Bunil, Buronil, Buronon, Butyrophenone, 4′-fluoro-4-(4-methylpiperidino)-, Fg 5111, Flubuperone, Melperona, Melperona [INN-Spanish], Melperone [INN:BAN:DCF], Melperonum, Melperonum [INN-Latin], Methylperone, Metylperon, Metylperonum, Unii-J8Wa3K39B7, γ-(4-Methylpiperidino)-p-fluorobutyrophenone
• CAS: 3575-80-2

Description

Melperone is used for the treatment of schizophrenia and other psychotic disorders. It is a dopamine antagonist that blocks dopamine receptors in the brain, which are believed to be responsible for symptoms of schizophrenia. Melperone also has a synergistic effect with levodopa, which is used to treat Parkinson's disease. Melperone may cause an increase in serum prolactin levels and lead to symptoms such as breast enlargement, decreased libido, and increased appetite in women. This drug should not be prescribed to geriatric patients with congestive heart failure or those who have a history of cardiac arrhythmias. The therapeutic range of melperone in human serum has been determined using HPLC analysis with UV detection at 254 nm.

• Brand: Biosynth

Chemical properties

• Molecular weight: 263.35 g/mol
• Formula: C₁₆H₂₂FNO
• Purity: Min. 95%
• InChI: InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3
• InChI key: InChIKey=DKMFBWQBDIGMHM-UHFFFAOYSA-N
• SMILES: CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1