2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)isopropoxyiminoacetate

CAS: 89604-92-2

Ref. 3D-FM25085

Product Information

• Name: 2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)isopropoxyiminoacetate
• Synonyms: 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid 1,1-dimethylethyl ester, (Z)-2-(2-aminothiazol-4-yl)-2-(2-t-butoxycarbonylprop-2-oxyimino) acetate, 1,1-Dimethylethyl 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]amino]oxy]-2-methylpropanoate, 2-Mercaptobenzothiazolyl (Z)-2-(2-aminothiazol-4-yl)-2-(2-t-butoxycarbonylprop-2-oxyimino) acetate, 2-Mercaptobenzothiazolyl-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)isopropoxyiminoacetate, 2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate, 2-Mercaptobenzothiazolyl-(Z)-(2-aminotiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyaminoacetate, Benzothiazolyl [2-(2-tert-butoxy-carbonylprop-2-oxdyimino)-2-(4-amino-thiazol-4-yl) thio acetate, Ceftazidime intermediate, Propanoic acid (Z)-2-[[[1-(2-amino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]amino]oxy]-2-methyl-1,1-dimethylethyl ester, Propanoic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]amino]oxy]-2-methyl-, 1,1-dimethylethyl ester, Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]amino]oxy]-2-methyl-, 1,1-dimethylethyl ester, (Z)-, Propanoic acid,2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)isopropoxyiminoacetate, S-2-Benzothiazolyl (Z)-2-(2-aminothiazol-4-yl)-2-(1-t-butoxycarbonyl-1-methyl)ethoxyiminothioacetate, S-2-benzothiazoyl-(Z)-2-(1-ter-butoxycanbonyl-1-methylethoxyimino)-4-thiazoleacetate, Taem, tert-butyl 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-(1,3-benzothiazol-2-ylsulfanyl)-2-oxoethylidene]amino}oxy)-2-methylpropanoate

Description

2-Mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)isopropoxyiminoacetate is a growth factor that binds to the epidermal growth factor receptor (EGFR), though not as strongly as EGF. It has been shown to stimulate the production of phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate by binding to the enzyme phosphatidylinositol 3,4,5-trisphosphate kinase. 2MBTSA inhibits the proliferation of tumor cells in culture and also prevents their migration. The compound was shown to be active against a wide range of cancers including breast cancer, prostate cancer, and lung cancer. Clinical studies have demonstrated that 2MBTSA can reduce pain associated with bone metastases in patients

• Brand: Biosynth

Chemical properties

• Molecular weight: 478.61 g/mol
• Formula: C₂₀H₂₂N₄O₄S₃
• Purity: Min. 95%
• InChI: InChI=1S/C20H22N4O4S3/c1-19(2,3)27-16(26)20(4,5)28-24-14(12-10-29-17(21)22-12)15(25)31-18-23-11-8-6-7-9-13(11)30-18/h6-10H,1-5H3,(H2,21,22)/b24-14-
• InChI key: InChIKey=RCZJVHXVCSKDKB-OYKKKHCWSA-N
• SMILES: CC(C)(C)OC(=O)C(C)(C)O/N=C(\C(=O)Sc1nc2ccccc2s1)c1csc(N)n1