2-Methylquinoxaline 1,4-dioxide
CAS: 6639-86-7
Ref. 3D-FM25947
| 1g | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
- 2-Methylquinoxaline N,N'-dioxide2-Methylquinoxaline di-N-oxideNSC 47509
- 2-Methyl-1-oxoquinoxalin-1-ium-4(1H)-olate
- 2-Methylquinoxaline N,N′-dioxide
- 2-Methylquinoxaline di-N-oxide
- 3-Methylquinoxaline-1,4-diium-1,4-bis(olate)
- 3-methyl-1-oxoquinoxalin-1-ium-4(1H)-olate
- NSC 47509
- NSC 47510
- Nsc 48949
- Quinoxaline, 2-methyl-, 1,4-dioxide
- See more synonyms
2-Methylquinoxaline 1,4-dioxide is a synthetic compound that is an analogue of the natural product quinoxaline. It has been shown to be effective against intestinal bacterial strains and tumour cell lines in vitro. 2-Methylquinoxaline 1,4-doxide has also been shown to have minimal inhibitory concentration against brain tumor cells.
2-Methylquinoxaline 1,4-dioxide is synthesised from potassium dichromate and methyl 2-methylquinoxalinato copper(II). This reaction requires stabilisers such as sodium carbonate or potassium carbonate. The functional theory states that the cytotoxic effect of 2-Methylquinoxaline 1,4-dioxide on cancer cells may be due to its ability to inhibit DNA synthesis and cell growth by binding to the copper ion in the active site of topoisomerase II.
