3-Methyl-2-butenoyl chloride

CAS: 3350-78-5

Ref. 3D-FM29933

Product Information

• Name: 3-Methyl-2-butenoyl chloride
• Synonyms: 2-Butenoyl chloride, 3-methyl-, 3,3-Dimethylacrylic acid chloride, 3,3-Dimethylacrylyl chloride, 3-Methylbut-2-Enoyl Chloride, 3-Methylcrotonoyl chloride, Crotonoyl chloride, 3-methyl-, Senecioyl chloride, β,β-Dimethylacrylic acid chloride, β,β-Dimethylacryloyl chloride, β,β-Dimethylacrylyl chloride, β-Methylcrotonoyl chloride, γ,γ-Dimethylacryloyl chloride
• CAS: 3350-78-5

Description

3-Methyl-2-butenoyl chloride is a coumarin derivative that was found to have significant cytotoxicity in vitro. It inhibits the synthesis of DNA and RNA and also induces decursin, which leads to the death of cancer cells. 3-Methyl-2-butenoyl chloride has been shown to be effective against cancer cells in a number of different tissues, including the skin, bladder, sarcoma cell, and bone. The compound's synthetic pathway has been elucidated through nuclear magnetic resonance spectroscopy (NMR) and it is thought that this may be due to its ability to inhibit the enzyme propionyl coenzyme A carboxylase. This enzyme catalyzes the conversion of propionyl coenzyme A into succinyl coenzyme A. 3-Methyl-2-butenoyl chloride is also known to have antiinflammatory properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 118.56 g/mol
• Formula: C₅H₇ClO
• Purity: Min. 95%