4-Methoxy-3-methylbenzeneboronic acid

CAS: 175883-62-2

Ref. 3D-FM29963

Product Information

• Name: 4-Methoxy-3-methylbenzeneboronic acid
• Synonyms: B-(4-METHOXY-3-METHYLPHENYL)BORONIC ACID, 4-Methoxy-3-methylphenylboronic acid

Description

4-Methoxy-3-methylbenzeneboronic acid is a boronic acid that is used in the synthesis of amides. It is synthesized by the cross-coupling reaction of an organolithium compound with 4-methoxybenzeneboronic acid. This synthetic intermediate can be hydrolyzed to form a chloride, which can then be converted to an amide by reacting with ammonia or primary amine.
4-Methoxy-3-methylbenzeneboronic acid has been shown to act as an inhibitor of dehydrogenase enzymes, such as 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, which are involved in the production of steroids from cholesterol. In addition, 4-methoxybenzeneboronic acid has been used for the stereoselective synthesis of chiral compounds and nitro compounds. The target enzyme specificity and stereoselect

• Brand: Biosynth

Chemical properties

• Molecular weight: 165.98 g/mol
• Formula: C₈H₁₁BO₃
• Purity: Min. 95%
• InChI: InChI=1S/C8H11BO3/c1-6-5-7(9(10)11)3-4-8(6)12-2/h3-5,10-11H,1-2H3
• InChI key: InChIKey=PXVDQGVAZBTFIB-UHFFFAOYSA-N
• SMILES: COc1ccc(B(O)O)cc1C