5-Methoxypyrazine-2-carboxylic acid
CAS: 40155-42-8
Ref. 3D-FM31315
1g | To inquire | ||
2g | To inquire | ||
5g | To inquire | ||
10g | To inquire | ||
500mg | To inquire |
Product Information
- 2-Pyrazinecarboxylic acid, 5-methoxy-
- 5-Methoxy-2-pyrazinecarboxylic acid
- Pyrazinecarboxylic acid, 5-methoxy-
- Pyrazinecarboxylicacid, 5-methoxy-
5-Methoxypyrazine-2-carboxylic acid (5MPCA) is a diastereoselective inhibitor of β-amyloid peptide aggregation. It has been shown to reduce the formation of β-amyloid in a pharmacodynamic study with significant reduction of Aβ40 and Aβ42 levels in cerebral spinal fluid. 5MPCA inhibits the enzyme β-secretase, which cleaves the amyloid precursor protein (APP) at the β site, leading to reduced production of β-amyloid. The inhibition of β-secretase by 5MPCA prevents Aβ from being generated and thereby reduces its level in cerebral spinal fluid.
Chemical properties
Technical inquiry about: 3D-FM31315 5-Methoxypyrazine-2-carboxylic acid
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