2-(4-methyl-piperazin-1-yl)-ethylamine

CAS: 934-98-5

Ref. 3D-FM35219

Product Information

• Name: 2-(4-methyl-piperazin-1-yl)-ethylamine
• Synonyms: 1-(2-Aminoethyl)-4-methylpiperazine, 1-Methyl-4-(2-aminoethyl)piperazine, 1-Piperazineethanamine, 4-methyl-, 2-(4-Methyl-1-piperazinyl)ethanamine, 2-(4-Methylpiperazin-1-yl)ethan-1-amine, 2-(4-Methylpiperazin-1-yl)ethanamine, 2-(4-Methylpiperazin-1-yl)ethylamine, 2-(4-Methylpiperazino)ethanamine, 213-296-3, 4-(2-Aminoethyl)-1-methylpiperazine, 4-Methyl-1-piperazineethanamine, Piperazine, 1-(2-aminoethyl)-4-methyl-

Description

2-(4-methyl-piperazin-1-yl)-ethylamine (4MPE) is a potent inhibitor of cell growth. It inhibits the proliferation of cancer cells by binding to and inhibiting the activity of two enzymes, DNA topoisomerase II and tyrosine kinases, which are necessary for cell division. 4MPE has been shown to be active on xenografts in mice, indicating that it can cross the blood brain barrier. This compound has also been shown to inhibit transpiration in plants and has potential as a probe for studying food chains. 4MPE was synthesized with an affinity for cancer cells and tested against a panel of animal tumor cells. It showed potent antiproliferative activity in vitro, but was not toxic to animals at high doses. This agent also had fluorescence properties that make it suitable for use as a fluorescent probe in biological research.

• Brand: Biosynth

Chemical properties

• Molecular weight: 143.23 g/mol
• Formula: C₇H₁₇N₃
• Purity: Min. 95%
• InChI: InChI=1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
• InChI key: InChIKey=GOWUDHPKGOIDIX-UHFFFAOYSA-N
• SMILES: CN1CCN(CCN)CC1