1-(4-Methoxybenzoyl)-piperazine

CAS: 94747-49-6

Ref. 3D-FM38810

Product Information

• Name: 1-(4-Methoxybenzoyl)-piperazine
• Synonyms: (4-Methoxyphenyl)(piperazin-1-yl)methanone, Methanone, (4-methoxyphenyl)-1-piperazinyl-

Description

1-(4-Methoxybenzoyl)-piperazine is an efficient and selective monoacylating agent for the acylation of amines. It can be used in organic synthesis as a building block for the synthesis of pharmaceuticals, agrochemicals, dyestuffs, and other chemicals. This compound is synthesized by reacting ethylenediamine with piperazine in the presence of a catalytic amount of aluminum chloride. The yield is high and reactions run smoothly without side reactions. The 1-(4-methoxyphenyl)piperazine product can be further reacted with various acyl halides to give desired monoacylated products.

• Brand: Biosynth

Chemical properties

• Molecular weight: 220.27 g/mol
• Formula: C₁₂H₁₆N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C12H16N2O2/c1-16-11-4-2-10(3-5-11)12(15)14-8-6-13-7-9-14/h2-5,13H,6-9H2,1H3
• InChI key: InChIKey=AWNXKUKDGIDDBE-UHFFFAOYSA-N
• SMILES: COc1ccc(C(=O)N2CCNCC2)cc1