Methyl 4-bromomethylbenzoate

CAS: 2417-72-3

Ref. 3D-FM38827

Product Information

• Name: Methyl 4-bromomethylbenzoate
• Synonyms: 4-(Bromomethyl)benzoic acid methyl ester, 4-(Bromomethyl)Benzoic Acid Methyl Ester, 4-(Carbomethoxy)benzyl bromide, 4-(Methoxycarbonyl)benzyl bromide, 4-Bromomethyl Benzoate, Alpha-Bromo-P-Toluic Acid Methyl Ester, Benzoic acid, 4-(bromomethyl)-, methyl ester, Methyl Alpha-Bromo-P-Toluate, Methyl P-(Bromomethyl)Benzoate, Methyl α-bromo-p-toluate, Nsc 83959, p-(Bromomethyl)benzoic acid methyl ester, p-(Carbomethoxy)benzyl bromide, p-(Methoxycarbonyl)benzyl bromide, p-Toluic acid, α-bromo-, methyl ester, α-Bromo-p-toluic acid methyl ester
• CAS: 2417-72-3

Description

Methyl 4-bromomethylbenzoate is an aryl halide with the chemical formula CHBr. It is an orally effective and selective apoptosis pathway inhibitor that blocks the release of tumor necrosis factor-α (TNF-α) induced by lipopolysaccharides in monocytes. Methyl 4-bromomethylbenzoate has also been shown to inhibit matrix metalloproteinase activity in vitro, which may be due to its ability to block the cleavage of proteoglycan precursors. The molecular modeling studies have revealed that this agent binds to DNA through a hydrophobic pocket, which inhibits transcription and replication. Methyl 4-bromomethylbenzoate has also been shown to be active against cancer cells and induce apoptosis through caspase activation and mitochondrial dysfunction.

• Brand: Biosynth

Chemical properties

• Molecular weight: 229.07 g/mol
• Formula: C₉H₉BrO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C9H9BrO2/c1-12-9(11)8-4-2-7(6-10)3-5-8/h2-5H,6H2,1H3
• InChI key: InChIKey=NLWBJPPMPLPZIE-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(CBr)cc1