3-N-Maleimidobenzoic acid

CAS: 17057-07-7

Ref. 3D-FM48820

Product Information

• Name: 3-N-Maleimidobenzoic acid
• Synonyms: 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acidN-(3-Benzoic acid)maleimide, (3-Carboxyphenyl)maleimide, 3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)benzoic acid, 3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1yl)-benzoic acid, 3-(2,5-Dioxo-2,5-Dihydro-Pyrrol-1-Yl)-Benzoic Acid, 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate, 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid, 3-Maleimidobenzoic acid, Benzoic acid, 3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, Benzoic acid, m-maleimido-, N-(3-Carboxyphenyl)maleimide, NSC 201626, m-Maleimidobenzoic acid

Description

3-N-Maleimidobenzoic acid is a chemical crosslinking agent that reacts with proteins through the formation of an amide bond. It has been shown to react with both actin subunits and human immunoglobulin. This molecule also reacts with spermatozoa, which are composed primarily of actin filaments, and is used in the preparation of polyclonal antibodies. 3-N-Maleimidobenzoic acid can be used to fix antigen onto a solid support for immunological purposes. It is also a cross-linking agent that can be used in cytochalasin B experiments to inhibit plastid activity in chloroplasts. 3-N-Maleimidobenzoic acid reacts with monoclonal antibodies by forming an amide bond, which can be used as a reaction product.

• Brand: Biosynth

Chemical properties

• Molecular weight: 217.18 g/mol
• Formula: C₁₁H₇NO₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H7NO4/c13-9-4-5-10(14)12(9)8-3-1-2-7(6-8)11(15)16/h1-6H,(H,15,16)
• InChI key: InChIKey=ZJGBFJBMTKEFNQ-UHFFFAOYSA-N
• SMILES: O=C(O)c1cccc(N2C(=O)C=CC2=O)c1