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O-Methyl-D-prolinol
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O-Methyl-D-prolinol

CAS: 84025-81-0

Ref. 3D-FM49611

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Estimated delivery in United States, on Friday 28 Jun 2024

Product Information

Name:
O-Methyl-D-prolinol
Synonyms:
  • (R)-2-Methoxymethylpyrrolidine
  • (2R)-2-(methoxymethyl)pyrrolidine
  • RMP
Description:

O-Methyl-D-prolinol is a molecule that belongs to the class of pharmaceutical drugs. It is synthesized by the alkylation of propiophenone with trifluoromethylated methyl iodide. O-Methyl-D-prolinol has been shown to inhibit the growth of P. aeruginosa, a bacterium that causes chronic respiratory infections in cystic fibrosis patients. This drug blocks bacterial DNA synthesis by inhibiting the enzyme OMP decarboxylase and blocking the formation of dUMP from dUTP. O-Methyl-D-prolinol has also been shown to be stereoselective, meaning it binds preferentially to one chiral form (S) of its target enzyme, while not binding at all to its mirror image (R). This allows for selective inhibition against bacteria that are resistant to other antibiotics.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
115.17 g/mol
Formula:
C6H13NO
Purity:
Min. 95%
Color/Form:
Clear Liquid
InChI:
InChI=1S/C6H13NO/c1-8-5-6-3-2-4-7-6/h6-7H,2-5H2,1H3/t6-/m1/s1
InChI key:
InChIKey=CHPRFKYDQRKRRK-ZCFIWIBFSA-N
SMILES:
COC[C@H]1CCCN1
MDL:
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Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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