4-(4-Methylpiperazino)benzaldehyde

CAS: 27913-99-1

Ref. 3D-FM50756

Product Information

• Name: 4-(4-Methylpiperazino)benzaldehyde
• Synonyms: 1-(4-Formylphenyl)-4-methylpiperazine4-(4-Methylpiperazino)benzenecarbaldehyde, 1-(4-Formylphenyl)-4-methylpiperazine, 4-(4-Formylphenyl)-1-Methylpiperazin-1-Ium, 4-(4-Methyl-1-piperazinyl)benzaldehyde, 4-(4-Methylpiperazin-1-Yl)Benzaldehyde, 4-(4-Methylpiperazin-1-yl)benzenecarboxaldehyde, Benzaldehyde, 4-(4-methyl-1-piperazinyl)-, Benzaldehyde, p-(4-methyl-1-piperazinyl)-

Description

4-(4-Methylpiperazino)benzaldehyde (MPBA) is a broad-spectrum antimicrobial that has been shown to have potent inhibition of bacterial efflux pumps. MPBA has also been shown to be a potent inhibitor of the multidrug efflux pump, P-glycoprotein, and its analogs. MPBA has been found to have hemolytic activity in the presence of human erythrocytes and a reactive functional group that may be involved in the binding process. The compound also shows potent inhibition of bacterial growth with MIC values ranging from 0.05 to 1 μg/mL for staphylococcus isolates. MPBA has been found to exhibit optical properties in the ultraviolet region, which may be useful for applications such as photodynamic therapy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.27 g/mol
• Formula: C₁₂H₁₆N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C12H16N2O/c1-13-6-8-14(9-7-13)12-4-2-11(10-15)3-5-12/h2-5,10H,6-9H2,1H3
• InChI key: InChIKey=PFODEVGLOVUVHS-UHFFFAOYSA-N
• SMILES: CN1CCN(c2ccc(C=O)cc2)CC1