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1-Methyl-5-nitro-1H-indazole
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1-Methyl-5-nitro-1H-indazole

CAS: 5228-49-9

Ref. 3D-FM50927

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Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
1-Methyl-5-nitro-1H-indazole
Synonyms:
  • 1-Methyl-5-nitroindazole
  • 1-Methyl-5-nitro-1H-benzopyrazole
  • 1-methyl-5-nitro-1H-indazole
  • 1H-Indazole, 1-methyl-5-nitro-
  • 5-Nitro-1-methylindazole
  • NSC 131656
Description:

1-Methyl-5-nitro-1H-indazole is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. It binds to the 16S ribosomal RNA, leading to inhibition of protein synthesis and cell death by inhibiting the production of proteins vital for cell division. The 1-methyl form has been shown to be effective against gram-negative bacteria, while the 5-nitro form is active against gram-positive bacteria. The nitro group on this molecule can alkylate DNA, which may lead to crosslinking with other bases in the DNA strand. This may lead to a red shift in its absorption spectrum due to an increase in conjugation length. 1-Methyl-5-nitro-1H-indazole has also been shown to produce fluorescence due to its solvatochromic properties.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
177.16 g/mol
Formula:
C8H7N3O2
Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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