2-(4-Methylphenoxy)Benzoic Acid

CAS: 21905-69-1

Ref. 3D-FM52898

Product Information

• Name: 2-(4-Methylphenoxy)Benzoic Acid
• CAS: 21905-69-1

Description

2-(4-Methylphenoxy)benzoic acid is a xanthone that is used as an intermediate in the production of dibenzofurans. It can be synthesized by reacting 4-methylphenol and benzoic acid in the presence of a base. The xanthone reacts with the phenolic hydrogen to form an intramolecular hydrogen bond, which then transfers to a nitrogen atom on the adjacent molecule. This reaction breaks the C=C bond and forms an aromatic transition state that can be stabilized by electron delocalization. In addition, 2-(4-methylphenoxy)benzoic acid has potent anti-inflammatory properties as it inhibits cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase (5LOX).

• Brand: Biosynth

Chemical properties

• Molecular weight: 228.24 g/mol
• Formula: C₁₄H₁₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C14H12O3/c1-10-6-8-11(9-7-10)17-13-5-3-2-4-12(13)14(15)16/h2-9H,1H3,(H,15,16)
• InChI key: InChIKey=GRUODACYFFPYCV-UHFFFAOYSA-N
• SMILES: Cc1ccc(Oc2ccccc2C(=O)O)cc1