4-Maleimidomethylcyclohexanecaroboxylic acid

CAS: 69907-67-1

Ref. 3D-FM54570

Product Information

• Name: 4-Maleimidomethylcyclohexanecaroboxylic acid
• Synonyms: Mal-AMCHC-OH, Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid

Description

4-Maleimidomethylcyclohexanecaroboxylic acid (4MAMC) is a bifunctional molecule that is conjugated to a polymer, which has the ability to bind with cellular antigens and target tissue. It is used in clinical chemistry because it can be detected at low concentrations. 4MAMC has been shown to reduce cirrhosis caused by chronic liver injury. 4MAMC also increases the uptake of coagulation factors and decreases the expression of prothrombin, which leads to an increase in clotting time. The localization of 4MAMC is determined by the type of polymer conjugate it is bound with; for example, when it binds with human serum albumin, it localizes on the surface of cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 237.25 g/mol
• Formula: C₁₂H₁₅NO₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C12H15NO4/c14-10-5-6-11(15)13(10)7-8-1-3-9(4-2-8)12(16)17/h5-6,8-9H,1-4,7H2,(H,16,17)
• InChI key: InChIKey=LQILVUYCDHSGEU-UHFFFAOYSA-N
• SMILES: O=C(O)C1CCC(CN2C(=O)C=CC2=O)CC1