2-Methyl-pentanedioic acid

CAS: 617-62-9

Ref. 3D-FM57991

Product Information

• Name: 2-Methyl-pentanedioic acid
• Synonyms: (2R)-2-methylpentanedioate, (2S)-2-methylpentanedioate, 2-MethylglutaricAcid, 2-Methylpentanedioic Acid, A-Methylglutaric Acid, Ai3-23452, Akos 237-134, Glutaric acid, 2-methyl-, Nsc 408456, Nsc 5941, Pentanedioic acid 2-methyl ester, Pentanedioic acid, 2-methyl-, (.+/-.)-, Rarechem Al Bo 0092
• CAS: 617-62-9

Description

2-Methyl-Pentanedioic acid is a metabolite that inhibits the enzyme acetyl-CoA carboxylase, which is involved in the synthesis of fatty acids and cholesterol. 2-Methyl-pentanedioic acid has been shown to inhibit the growth of bacteria by irreversible inhibition of the acetyl-CoA carboxylase enzyme. This amino acid is used as a substrate molecule for kinetic studies of bacterial mutases, which are enzymes that catalyze transfer reactions involving amino acids. The analytical method for measuring 2-methyl-pentanedioic acid in biological samples involves gas chromatography with flame ionization detection. Mutations in the gene encoding this enzyme can result in metabolic disorders such as hyperlipidemia and hyperglycemia.

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.14 g/mol
• Formula: C₆H₁₀O₄
• Purity: Min. 95%
• Color/Form: White/Off-White Solid
• InChI: InChI=1S/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)
• InChI key: InChIKey=AQYCMVICBNBXNA-UHFFFAOYSA-N
• SMILES: CC(CCC(=O)O)C(=O)O