3-Methylbenzenesulfonyl chloride
CAS: 1899-93-0
Ref. 3D-FM59089
2g | To inquire | ||
5g | To inquire | ||
10g | To inquire | ||
25g | To inquire | ||
50g | To inquire |
Product Information
- 3-Toluenesulfonyl chloride
- M-toluenesulfonyl chloride
- 3-Methylbenzenesulfonyl Chloride
- m-Toluenesulphonyl chloride
3-Methylbenzenesulfonyl chloride is a synthetic compound that is a potent 5-HT7 receptor agonist. It has been shown to stimulate locomotor activity and induce convulsions in mice. 3-Methylbenzenesulfonyl chloride was found to have a high safety profile in preclinical studies and did not show any signs of neurotoxicity. The molecule also has functional effects on the 5-HT7 receptor, including partial agonism, antagonism, and inverse agonism. 3-Methylbenzenesulfonyl chloride binds to the pyrazole ring of the 5-HT7 receptor by ring opening or hydrogen bonding with an amide nitrogen atom in its peptidomimetic form. This binding induces conformational changes in the 5-HT7 receptor that lead to G protein activation and downstream signaling pathways that result in antiproliferative effects.
Chemical properties
Technical inquiry about: 3D-FM59089 3-Methylbenzenesulfonyl chloride
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